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  • 検索条件 : 絞込み (MeSH = Guanine Nucleotide Exchange Factors / metabolism)
生物種 リソース名 タイトル
線虫 tm4024 , tm469 Dendrite regeneration in C. elegans is controlled by the RAC GTPase CED-10 and the RhoGEF TIAM-1.
遺伝子材料 , ヒト・動物細胞 pmStr-C1-Vps9d1 (RDB19825) , pmStr-C1-Vps9d1-Y628A (YA) (RDB19826) , COS-7(RCB0539) Vps9d1 regulates tubular endosome formation through specific activation of Rab22A.
ヒト・動物細胞 C6(RCB2854) , RCR-1(RCB1456) Central nervous system specific high molecular weight ALS2/alsin homophilic complex is enriched in mouse brain synaptosomes.
ヒト・動物細胞 Saos-2(RCB0428) The survival and proliferation of osteosarcoma cells are dependent on the mitochondrial BIG3-PHB2 complex formation.
実験動物マウス RBRC04421 The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts.
遺伝子材料 CSII-CMV-MCS-IRES2-Bsd (RDB04385) Wnt5a signaling promotes apical and basolateral polarization of single epithelial cells.
ヒト・動物細胞 B16/BL6(RCB2638) CD47 promotes T-cell lymphoma metastasis by up-regulating AKAP13-mediated RhoA activation.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Kinase activity-independent role of EphA2 in the regulation of M-phase progression.
ヒト・動物細胞 NRK49F(RCB0112) The signal pathway for the repressive effect of dipyridamole on myofibroblast transdifferentiation.
線虫 tm2760 , tm5205 , tm2255 , tm6137 Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals.
ショウジョウバエ Rap1, Canoe and Mbt cooperate with Bazooka to promote zonula adherens assembly in the fly photoreceptor.
線虫 tm1447 SAC-1 ensures epithelial endocytic recycling by restricting ARF-6 activity.
イネ Induced mutation lines Selective sets of mRNAs localize to extracellular paramural bodies in a rice glup6 mutant.
線虫 tm752 The SH3 domain of UNC-89 (obscurin) interacts with paramyosin, a coiled-coil protein, in Caenorhabditis elegans muscle.
線虫 tm1447 , tm2523 , tm2616 LET-413/Erbin acts as a RAB-5 effector to promote RAB-10 activation during endocytic recycling.
線虫 tm1516 The HECT Family Ubiquitin Ligase EEL-1 Regulates Neuronal Function and Development.
遺伝子材料 pcDNA3/hArf5(WT)-HA (RDB15359) , pcDNA3/hArf5(Q71L)-HA (RDB15360) , pcDNA3/hArf5(T31N)-HA (RDB15361). Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.
イネ Induced mutation lines Guanine nucleotide exchange factor 2 for Rab5 proteins coordinated with GLUP6/GEF regulates the intracellular transport of the proglutelin from the Golgi apparatus to the protein storage vacuole in rice endosperm.
線虫 tm3203 , tm2916 , tm2926 , tm3214 Neuronally expressed Ras-family GTPase Di-Ras modulates synaptic activity in Caenorhabditis elegans.
線虫 tm597 Integrin α PAT-2/CDC-42 signaling is required for muscle-mediated clearance of apoptotic cells in Caenorhabditis elegans.