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  • Search Condition : Filter (MeSH = Guanine Nucleotide Exchange Factors / metabolism)
Species Resource
C.elegans tm2807 , tm2927 The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration.
Xenopus tropicalis XRASGRP2 is essential for blood vessel formation during Xenopus development.
C.elegans tm920 , tm1320 , tm584 , tm847 , tm935 , tm933 , tm920 , tm246 Genetic analysis of lysosomal trafficking in Caenorhabditis elegans.
DNA material pCMV-VSV-G-RSV-REV (RDB04393) Transcription factor 8 activates R-Ras to regulate angiogenesis.
Yeast FY11065 , Plasmid library Cooperation between the septins and the actomyosin ring and role of a cell-integrity pathway during cell division in fission yeast.
Yeast ? CUE domain-containing protein Vps901 is required for vacuolar protein transport in Schizosaccharomyces pombe.
DNA material X. laevis whole embryo(stage 25) EST clones XL099E15. Regulation of G-protein signaling via Gnas is required to regulate proximal tubular growth in the Xenopus pronephros.
Drosophila Reduced cell number in the hindgut epithelium disrupts hindgut left-right asymmetry in a mutant of pebble, encoding a RhoGEF, in Drosophila embryos.
Drosophila Age-dependent deterioration of locomotion in Drosophila melanogaster deficient in the homologue of amyotrophic lateral sclerosis 2.
C.elegans tm1516 The HECT Family Ubiquitin Ligase EEL-1 Regulates Neuronal Function and Development.
DNA material pEF-FLAG-mouse Rab8A (RDB14271) , pEF-FLAG-mouse Rab10 (RDB14272) , pEGFP-C1-mouse Rab8A (RDB14273) , pEGFP-C1-mouse Rab10 (RDB14274) , pEGFPC1-mouse Rab8A-Q67L - constitutive active (RDB14275) , pEGFPC1-mouse Rab8A-T22N - constitutive negative (RDB14276) , pEGFPC1-mouse Rab10-Q68L - constitutive active (RDB14277) , pEGFPC1-mouse Rab10-T23N - constitutive negative (RDB14278) , pEGFP-C1-mouse Rabin8-delGEF-300-305 - GEF-activity/Rab11-binding-deficient (RDB14279) , pEGFP-C1-mouse Rabin8-delGEF - GEF-activity-deficient (RDB14280) , ... Rabin8 regulates neurite outgrowth in both GEF activity-dependent and -independent manners.
C.elegans tm4024 Developmental Function of the PHR Protein RPM-1 Is Required for Learning in Caenorhabditis elegans.
C.elegans tm3480 RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal development.
C.elegans tm1949 , tm1556 , tm1826 Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans.
C.elegans tm4246 , tm3467 , tm4024 , tm2807 Systematic analyses of rpm-1 suppressors reveal roles for ESS-2 in mRNA splicing in Caenorhabditis elegans.
C.elegans tm3663 Mechanisms of CDC-42 activation during contact-induced cell polarization.
C.elegans tm1512 Disruption of endocytic pathway regulatory genes activates autophagy in C. elegans.
C.elegans tm2784 RAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegans.
Mice B6.Cg-Tg(Drd2-YFP)364-5(RBRC02332) , C57BL/6J-Tg(mDrd1-YFP)680-1Koba (RBRC03111) , B6;129S-Rap1a<tm1Morz> Rap1b<tm1Morz>(RBRC04720) Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.
DNA material pEF-LRRK2-FLAG-His (RDB13973) , pEF-HERC2 (RDB13974) , pEF-NEURL4 (RDB13975) , pEGFP-C-HERC2 (RDB13976) , pEGFP-C-NEURL4 (RDB13977) , pcDNA3-NEURL4-FLAG-His (RDB13978) , pcDNA3-FLAG-HERC2 (RDB13979). The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.