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論文 - 一覧

  • 19 Hits
  • 検索条件 : 絞込み (MeSH = Lactams, Macrocyclic / pharmacology)
生物種 リソース名 タイトル
ヒト・動物細胞 Ba/F3 NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations.
ヒト・動物細胞 Ba/F3(RCB0805) Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.
ヒト・動物細胞 Ba/F3 Two novel ALK mutations mediate acquired resistance to the next-generation ALK inhibitor alectinib.
ヒト・動物細胞 Ba/F3 Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer.
ヒト・動物細胞 PC-9(RCB4455) Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
ヒト・動物細胞 Ba/F3 The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models.
ショウジョウバエ Little effect of HSP90 inhibition on the quantitative wing traits variation in Drosophila melanogaster.
一般微生物 JCM 4427 New geldanamycin analogs from Streptomyces hygroscopicus.
ヒト・動物細胞 HL60(RCB0041) Rubratoxin-B-induced secretion of chemokine ligands of cysteine-cysteine motif chemokine receptor 5 (CCR5) and its dependence on heat shock protein 90 in HL60 cells.
ヒト・動物細胞 HSP90 is crucial for regulation of LAT expression in activated T cells.
シロイヌナズナ / 植物培養細胞・遺伝子 rpc00008 Heat shock protein 90 acts in brassinosteroid signaling through interaction with BES1/BZR1 transcription factor.
ヒト・動物細胞 HFL-III(RCB0523) , SQ-5(RCB0110) The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells.
ヒト・動物細胞 SK-N-SH(RCB0426) Inhibition of heat shock protein 90 attenuates adenylate cyclase sensitization after chronic morphine treatment.
ヒト・動物細胞 IEC 6(RCB0993) Evidence for enhanced cytoprotective function of HSP90-overexpressing small intestinal epithelial cells.
一般微生物 JCM 4427 Rational biosynthetic engineering for optimization of geldanamycin analogues.
酵母 NA Comprehensive screening of human genes with inhibitory effects on yeast growth and validation of a yeast cell-based system for screening chemicals.
遺伝子材料 pCMV-MAZ pCMV-MAZi (RDB03219) Mechanisms by which interleukin-6 regulates prostate-specific antigen gene expression in prostate LNCaP carcinoma cells.
ショウジョウバエ Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones.
シロイヌナズナ / 植物培養細胞・遺伝子 rpc00008 The 26S proteasome function and Hsp90 activity involved in the regulation of HsfA2 expression in response to oxidative stress.