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  • Search Condition : Filter (MeSH = Telomerase / genetics)
Species Resource
Human and Animal Cells HOS , OST , Saos-2 Analysis of telomerase activity and telomere length in bone and soft tissue tumors.
Yeast FY7512(JY741) , FY7499(JY746) , FY17233(YO001) , FY17234(YO004) , FY14174(JK805) , FY17235(YO005) Fission yeast Taz1 and RPA are synergistically required to prevent rapid telomere loss.
C.elegans tm750 , tm1203 , tm1524 , tm1620 End joining at Caenorhabditis elegans telomeres.
DNA material CSII-CMV-RfA-IRES2-Venus (RDB04388) Cancer cell invasion driven by extracellular matrix remodeling is dependent on the properties of cancer-associated fibroblasts.
Human and Animal Cells Telomerase activation as a repair response to radiation-induced DNA damage in Y79 retinoblastoma cells.
Human and Animal Cells Molecular mechanisms for the p38-induced cellular senescence in normal human fibroblast.
Human and Animal Cells Identification of non-coding RNAs associated with telomeres using a combination of enChIP and RNA sequencing.
DNA material CSII-CMV-RfA (RDB04386) , CSII-EF-RfA (RDB04387). A human cancer xenograft model utilizing normal pancreatic duct epithelial cells conditionally transformed with defined oncogenes.
DNA material CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase.
Human and Animal Cells Mechanism for the reduction of telomerase expression during muscle cell differentiation.
Human and Animal Cells GE1 (RCB1709) Establishment of human dental epithelial cell lines expressing ameloblastin and enamelin by transfection of hTERT and cdk4 cDNAs.
Medaka d-rR.YHNI , FLFII (MT109) Tert expression and telomerase activity in gonads and somatic cells of the Japanese medaka (Oryzias latipes).
Human and Animal Cells MKN7(RCB0999) New NCI-N87-derived human gastric epithelial line after human telomerase catalytic subunit over-expression.
DNA material pIDT-SMART(C-TSC) (RDB14136) Dramatic increase in expression of a transgene by insertion of promoters downstream of the cargo gene.
Human and Animal Cells Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells.
C.elegans tm1153 , tm849 , tm5409 RNA surveillance is required for endoplasmic reticulum homeostasis.
DNA material CSII-CMV-RfA (RDB04386) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.
DNA material pcDNA3_FLAG-TPP1 (RDB15160) , pcDNA3_FLAG-TPP1(S255A) (RDB15161) , pcDNA3_FLAG-TPP1(S332A) (RDB15162) , pcDNA3_FLAG-TPP1(T399A) (RDB15163) , pcDNA3_HA-NEK6 (RDB15164) , pcDNA3_HA-NEK7 (RDB15165). NEK6-mediated phosphorylation of human TPP1 regulates telomere length through telomerase recruitment.
C.elegans tm1579 , tm1400 , tm1620 Caenorhabditis elegans POT-2 telomere protein represses a mode of alternative lengthening of telomeres with normal telomere lengths.
C.elegans tm1620 , tm1400 Caenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways.