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  • Search Condition : Filter (MeSH = Telomere / metabolism*)
Species Resource Title
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway.
C.elegans tm1620 , tm1400 Caenorhabditis elegans POT-1 and POT-2 repress telomere maintenance pathways.
C.elegans tm1620 Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans.
C.elegans tm1620 , tm1400 The shelterin protein POT-1 anchors Caenorhabditis elegans telomeres through SUN-1 at the nuclear periphery.
Human and Animal Cells 3'-Azido-2',3'-dideoxynucleoside 5'-triphosphates inhibit telomerase activity in vitro, and the corresponding nucleosides cause telomere shortening in human HL60 cells.
Human and Animal Cells Sequence-specific alkylation of double-strand human telomere repeat sequence by pyrrole-imidazole polyamides with indole linkers.
Yeast S. pombe strains ? Timeless protection of telomeres.
Yeast ? Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing.
Yeast FY16194 , MY444 Long G2 accumulates recombination intermediates and disturbs chromosome segregation at dysfunction telomere in Schizosaccharomyces pombe.
DNA material S. pombe YFP-FLAG-His plasmid SpYFH27C12 (SPW090860) , SpYFH26G09 (SPW090553) , SpYFH36C12 (SPW094460). Fission yeast Cactin restricts telomere transcription and elongation by controlling Rap1 levels.
Yeast FY14150 , FY14135 , FY14283 , FY14283 , FY14256 SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.
Yeast FY29231(SSK61-3A) , FY29240(SMY107-3D) , FY29250(SMY77-3B) , FY29251(SMY98-1C) , FY29311(SMY49-2B) , FY29332(SKTT31-1) Microtubule-organizing center formation at telomeres induces meiotic telomere clustering.
Yeast FY18345(JK317) , FY7030(JK2325) , FY7796(JK2327) , FY13064(JK2326) , FY12806(JP1550) , FY18377(HT340) Telomere-nuclear envelope dissociation promoted by Rap1 phosphorylation ensures faithful chromosome segregation.
Yeast BYP6216(pAH52) , BYP367(pDH3) , pDH5? , BY25908(KM411) , BY25909(KM412) , BY25910(KM413) , BY25911(KM414) , BY25913(KM1067) , BY25914(KM1070) , BY25905(KH123) Ribosome biogenesis factors bind a nuclear envelope SUN domain protein to cluster yeast telomeres.
Yeast TA646 , TA746 ? TOR complex 2 controls gene silencing, telomere length maintenance, and survival under DNA-damaging conditions.
Yeast FY15617 , FY8026 , FY8033 Ccq1p and the condensin proteins Cut3p and Cut14p prevent telomere entanglements in the fission yeast Schizosaccharomyces pombe.
Arabidopsis / Cultured plant cells, genes rpc00008 Arabidopsis replication protein A 70a is required for DNA damage response and telomere length homeostasis.
DNA material pUCAlu (RDB01038) Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres.
C.elegans tm750 , tm1203 , tm1524 , tm1620 End joining at Caenorhabditis elegans telomeres.
C.elegans tm1400 , tm1620 C. elegans telomeres contain G-strand and C-strand overhangs that are bound by distinct proteins.