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  • Search Condition : Filter (MeSH = ADP-Ribosylation Factors / metabolism*)
Species Resource
DNA material B6N BAC Mouse (RDB07573) B6Ng01-089N24 , CSII-EF-MCS (RDB04378) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) , CS-RfA-EVBsd (RDB06090) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures.
Human and Animal Cells Rhythmic control of the ARF-MDM2 pathway by ATF4 underlies circadian accumulation of p53 in malignant cells.
C.elegans tm2322 Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans.
Yeast TN214? ADP-ribosylation factor arf6p may function as a molecular switch of new end take off in fission yeast.
DNA material pcDNA3 FLAG hATF2 WT (RDB06038) Phosphorylation of Activation Transcription Factor-2 at Serine 121 by Protein Kinase C Controls c-Jun-mediated Activation of Transcription.
DNA material pcDNA3/hArf1(WT)-HA (RDB15337) , pcDNA3/mArf1(Q71L)-HA (RDB15338) , pcDNA3/mArf1(T31N)-HA (RDB15339) , pEGFP-N3/hArf1(WT)-EGFP (RDB15340) , pcDNA3/hArf3(WT)-HA (RDB15341) , pcDNA3/mArf3(Q71L)-HA (RDB15342) , pcDNA3/mArf3(T31N)-HA (RDB15343) , pEGFP-N3/hArf3-EGFP (RDB15344). ARF1 and ARF3 are required for the integrity of recycling endosomes and the recycling pathway.
DNA material pcDNA3/hArf1(WT)-mCherry (RDB15345) , pcDNA3/hArf3-mCherry (RDB15346) , pcDNA3/hArf5(WT)-mCherry (RDB15347) , pEGFP-N3/hArf5(WT)-EGFP (RDB15348) , pcDNA3/hArf6(WT)-HA (RDB15349) , pcDNA3/hArf6(Q67L)-HA (RDB15350) , pcDNA3/hArf6(T27N)-HA (RDB15351) , pcDNA3/hArf6(WT)-mCherry (RDB15352) , pEGFP-N3/hArf6(WT)-EGFP (RDB15353). Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis.
DNA material pCAG/hArf4(WT)-HA (RDB15354) , pCAG/hArf4(Q71L)-HA (RDB15355) , pCAG/hArf4(T31N)-HA (RDB15356) , pCAG/hArf4(WT)-mCherry (RDB15357) , pCAG/hArf4(WT)-EGFP (RDB15358). ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus.
DNA material pcDNA3/hArf5(WT)-HA (RDB15359) , pcDNA3/hArf5(Q71L)-HA (RDB15360) , pcDNA3/hArf5(T31N)-HA (RDB15361). Class I Arfs (Arf1 and Arf3) and Arf6 are localized to the Flemming body and play important roles in cytokinesis.
DNA material pcDNA4c/His-Xpress-HA-hBIG1(WT) (RDB15362) , pcDNA4c/His-Xpress-HA-hBIG1(E793K) (RDB15363) , pcDNA4c/His-Xpress-HA-hBIG2(WT) (RDB15364) , pcDNA4c/His-Xpress-HA-hBIG2(E738K) (RDB15365). Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes.
DNA material pGEX-4T-2/hGGA1(GAT) (RDB15366) , pGEX-4T-2/hGGA3(GAT) (RDB15367). GGA proteins associate with Golgi membranes through interaction between their GGAH domains and ADP-ribosylation factors.
DNA material pmStr-N1-mouse Arf6 (RDB15387) , pEGFP-C1-mouse centaurin-b2-N610A/N691A (RDB15384). Rab35 regulates Arf6 activity through centaurin-β2 (ACAP2) during neurite outgrowth.
Human and Animal Cells Clathrin dependent endocytosis of E-cadherin is regulated by the Arf6GAP isoform SMAP1.