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  • 検索条件 : 絞込み (MeSH = Intracellular Signaling Peptides and Proteins / genetics)
生物種 リソース名 タイトル
実験動物マウス RBRC02759 Rubicon regulates A2E-induced autophagy impairment in the retinal pigment epithelium implicated in the pathology of age-related macular degeneration.
メダカ Overexpression of human SAMD9 inhibits protein translation and alters MYC signaling resulting in cell cycle arrest.
ゼブラフィッシュ UAS:GFP Identification of renal stem cells in zebrafish.
実験動物マウス RBRC01834 ARMC5 selectively degrades SCAP-free SREBF1 and is essential for fatty acid desaturation in adipocytes.
ゼブラフィッシュ UAS:GFP Endothelial Notch signalling limits angiogenesis via control of artery formation.
ショウジョウバエ HMS00067 SUMOylation of Warts kinase promotes neural stem cell reactivation.
実験動物マウス RBRC10762 Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice.
実験動物マウス RBRC01765 Loss of Tob1 promotes muscle regeneration through muscle stem cell expansion.
遺伝子材料 CSII-CMV-MCS-IRES2-Venus (RDB04383) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Insulin-induced genes INSIG1 and INSIG2 mediate oxysterol-dependent activation of the PERK-eIF2α-ATF4 axis.
遺伝子材料 CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (REB04394) CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP.
遺伝子材料 pCAGGS (RDB08938) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues.
ショウジョウバエ DGRC#119186 , DGRC#119187 Expression of Human Mutant Preproinsulins Induced Unfolded Protein Response, Gadd45 Expression, JAK-STAT Activation, and Growth Inhibition in Drosophila.
酵母 FY9899 Rcn1, the fission yeast homolog of human DSCR1, regulates arsenite tolerance independently from calcineurin.
ショウジョウバエ DGRC#115288 The Drosophila tumour suppressor Lgl and Vap33 activate the Hippo pathway through a dual mechanism.
ヒト・動物細胞 MKN45(RCB1001) Tribbles Genes in Gastric Cancer: A Tumor-Suppressive Role for TRIB2.
酵母 FY21033 The Hsp90 cochaperone TTT promotes cotranslational maturation of PIKKs prior to complex assembly.
線虫 tm4909 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
線虫 tm2960 PQN-59 antagonizes microRNA-mediated repression during post-embryonic temporal patterning and modulates translation and stress granule formation in C. elegans.
ショウジョウバエ 9293Ra-2  Tctp, a unique Ing5-binding partner, inhibits the chromatin binding of Enok in Drosophila.
酵母 Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.